December 2017
David Craig, PharmD | Editor

Funding Announcements

Mechanisms, Models, Measurement, and Management in Pain Research (R01 Clinical Trial Optional)

New advances are needed in every area of pain research, from the micro perspective of molecular sciences to the macro perspective of behavioral and social sciences. Although great strides have been made in some areas, such as the identification of neural pathways of pain, the experience of pain and the challenge of treatment have remained uniquely individual and unsolved. Furthermore, our understanding of how and why individuals transition to a chronic pain state after an acute injury is limited.

Research to address these issues conducted by interdisciplinary and multidisciplinary research teams is strongly encouraged, as is research from underrepresented, minority, disabled, or women investigators. Applicants may begin submitting applications January 6, 2018, and must complete their applications by 5 pm in their local time zone on February 5, 2018, to meet the cycle I deadline.

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NIH Development of a Device to Objectively Measure Pain (R43/R44)

The National Institutes of Health (NIH) encourages turning Small Business Innovation Research into the development of a technology/device that objectively indicates the presence and level of pain. Many of the recent advances in the development of pain measures have been made because of new and improved technologies. Because of these developments, NIH believes it is feasible to develop clinical tools to measure biomarkers or surrogate markers for the presence of acute or chronic pain. Tools like this would improve clinical pain research and treatment and provide more personalized treatment options for people in pain that do not rely on opioids.

United States small business concerns (SBCs) are eligible to apply for this grant. SBCs must submit applications no later than 5 pm in their local time zone on December 5, 2017.

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Mechanistic Studies of Pain and Alcohol Dependence (R01)

An association between chronic pain conditions and alcohol dependence has been revealed in numerous studies with episodes of alcohol abuse antedating chronic pain in some people and alcohol dependence emerging after the onset of chronic pain in others. Pain transmission and alcohol’s reinforcing effects share overlapping neural substrates, giving rise to the possibility that chronic pain states significantly affect alcohol use patterns and promote the development of dependence and addiction. In addition, long-term alcohol intoxication and alcohol dependence induce pain symptoms and may exacerbate chronic pain arising from other sources.

The objective of this funding opportunity announcement is to understand genetic, pharmacological, and learning mechanisms underlying the association between the propensity to drink alcohol excessively and pain responses. Applicants must complete their applications by 5 pm in their local time zone on February 5, 2018, to meet the cycle I deadline.

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Mayday Fund Announces New Fellowhship Program

The new fellowship, The Mayday Pain & Society Fellowship: Communicating Science & Improving Care, will train 10-12 clinicians and researchers who are passionate about improving pain care and who are dedicated to building communications skills and strategies aimed at reducing human suffering from acute and chronic pain.

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